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Hepatitis B and mental health

21/5/2020

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​First published on Hepatitis Australia's website in May 2020
People with chronic hepatitis B have higher rates of depression and anxiety than the general population [1].
​

Let’s have a look at why this happens, and what we can do about it.

Reacting to your diagnosis

Adjustment to having a chronic (lifelong) disease may mean having to [2]:
  • learn about hepatitis
  • make lifestyle changes
  • decide about disclosure to others
  • decide on whether to take antiviral therapy. 

Research [3] has found that many people worry about getting liver cancer or infecting others, and that these concerns could increase the risk of mental health problems, particularly depression. Not understanding enough about hepatitis B or having no one to confide in can also cause social isolation and affect mental health [4].

Hepatitis B treatment

There is no cure yet for chronic hepatitis B, but there are medications which can control the virus and reduce the risk of serious complications from the condition. However, like all medications, the treatment for hepatitis B can cause side-effects for some people, including affecting your mental health. This is something you should discuss with your doctor, as well as whether you’d like any additional support during your treatment.
There are two main options for treatment [5]. Usually, the preferred option is nucleoside analogues (NAs), such as tenofovir and entecavir. These have fewer side effects than interferon, but often need to be taken for a long time, or even for life. Pegylated interferon (PEG-IFN) is an alternative and is usually given over 48 weeks.

Researchers [6] reviewed studies of people on interferon, and found: 
  • significant depression occurred in 5% to 15% of people, with 21% to 58% experiencing milder symptoms
  • anxiety was found in 1.4% to 3.3% of people. 

It is also possible that a history of depression, anxiety, bipolar disorder or post-traumatic stress disorder (PTSD), combined with interferon may cause worsening symptoms, or relapse [2]. 

Now let’s look at how to get help. 

Learn and connect

Learning about hepatitis B is a good way of combatting misconceptions. Great resources include the Hepatitis Australia website and the National Hepatitis Infoline (1800 437 222), which directs you to the community-based hepatitis organisation in your state or territory who provide friendly and confidential help.

In addition you can look at the Hep B Help website which has links to hepatitis B organisations plus multilingual factsheets, audio and video resources too.

You could also contact the hepatitis organisation in your state or territory and perhaps link up with people who have similar experiences. Alternatively, you could join an online forum like Hep Forums.
​

Talk to your partner, friends and family. By sharing your knowledge, you can reduce stigma - which might otherwise isolate you or interfere with you receiving treatment - while getting the support you need. You can read these tips on telling others you have hepatitis.

Get healthy

Eat a healthy, balanced diet and maintain a healthy weight. Avoid alcohol and smoking. You should talk to your doctor before using any non-prescription drugs or supplements.

Try to keep to a regular sleep pattern and regular exercise.
​

For general support for mental health you can check out Head To Health as well as Lifeline and Beyond Blue. If you need more support, don’t forget you can speak with your GP, specialist or ask for a referral to a psychologist or psychiatrist.

Medications and talking therapy

When mental health issues arise, many people find it helps see a psychologist for one‑to‑one, confidential talking therapy. Sessions usually include learning about the mental health condition, why it has happened and why it has persisted. The psychologist can work with you to use tools like relaxation, mindfulness and cognitive behavioural therapy (CBT) as a way of coping with difficult emotions [7,8].

It is also thought that antidepressants and anti-anxiety medications can work well for interferon-related depression and anxiety [9,10].

Pre-existing psychiatric medication may need to be changed or adjusted during antiviral treatment, for example to one less toxic to the liver. Psychiatric medications and support might need to continue for at least 6 to 12 weeks after finishing antiviral treatment [10].
​

For people at higher risk for depression, such as those with a history of depression or alcohol overuse, pre-emptive treatment with antidepressants can be started before beginning antiviral therapy [10].

References

  1. Enescu, A., 2014. Psychosocial Issues in Patients with Chronic Hepatitis B and C. Current Health Sciences Journal, [Online]. 40(2), 93–96. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340448/ [Accessed 22 April 2020]. 
  2. Substance Abuse and Mental Health Services Administration. Addressing Viral Hepatitis in People With Substance Use Disorders. Treatment Improvement Protocol (TIP) Series 53. HHS Publication No. (SMA) 11-4656. Rockville, MD: Substance Abuse and Mental Health Services Administration, 2011.
  3. Hajarizadeh, B., 2016. Hepatitis B-Related Concerns and Anxieties Among People With Chronic Hepatitis B in Australia. Hepatitis Monthly, [Online]. 16(6), e35566. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010884/ [Accessed 22 April 2020].
  4. Chan H, Yu CS, Li SY. Psychiatric morbidity in Chinese patients with chronic hepatitis B infection in a local infectious disease clinic. East Asian Arch Psychiatry. 2012;22(4):160-168
  5. ASHM. 2018. Treatment of chronic hepatitis B virus infection. [ONLINE] Available at: https://www.hepatitisb.org.au/treatment-of-chronic-hepatitis-b-virus-infection/. [Accessed 22 April 2020].
  6. Coman, H., 2013. Psychiatric Adverse Effects Of Interferon Therapy. Medicine and Pharmacy Reports, [Online]. 86(4), 318–320. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462448/ [Accessed 22 April 2020].
  7. American Psychiatric Association. Practice guideline for the treatment of patients with major depressive disorder. 3rd ed. Arlington, VA: Author; 2010. Retrieved March 4, 2011,
  8. Wilson MP, Castillo EM, Batey AM. Hepatitis C and depressive symptoms: Psychological and social factors matter more than liver injury. International Journal of Psychiatry in Medicine. 2010;40(2):199–215.
  9. Hu, C., 2017. Depression and anxiety caused by pegylated interferon treatment in patients with chronic hepatitis B and the therapeutic effects of escitalopram and alprazolam. Journal of Southern Medical University, [Online]. 20;37(9), 1201-1205. Available at: https://www.ncbi.nlm.nih.gov/pubmed/28951362 [Accessed 22 April 2020].
  10. Schaefer M, Mauss S. Hepatitis C treatment in patients with drug addiction: Clinical management of interferon-alpha-associated psychiatric side effects. Current Drug Abuse Reviews. 2008;1(2):177–187
#hepatitisB #HepB #HepFreeAus @ASHMMedia @NO_hep @Hep_Alliance
@HepAus @LifelineAust @beyondblue #mentalhealth #depression #anxiety #stigma 
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Hepatitis B and relationships

25/3/2020

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Photo by Shelby Deeter on Unsplash
​First published on Hepatitis Australia's website in March 2020
"Having HBV is only a small facet of who you are, and not a reason to give up on a loving relationship. A partner who accepts you as you are and wants the best for you is someone who will not see HBV as a barrier to getting to know you.”

​– Lindsey [1], member of the Hepatitis B Information and Support List, Hepatitis B Foundation blog
Although most people get hepatitis B at birth, it can be transmitted in other ways including sex. This article contains information about how it is spreads, and how you can keep your partner safe.

How Hepatitis B is spread through sex

Hepatitis B contained in blood, semen or other fluids can be spread through unprotected vaginal, anal or oral sex. As it is very infectious, it transmits easily through breaks in the skin or mucous membranes (the lining of the nose, mouth, eyes and other soft tissues) [2].
​
We also need to remember that hepatitis B infection can occur through non-sexual contact such as sharing toothbrushes, razors or contact with an infected open wound.
​
However, it is not spread through normal hugging or kissing, or sharing meals, showers or toilets with someone who has hepatitis B [3].

How can we prevent the spread of hepatitis B?

The best way to prevent hepatitis B infection, is to get vaccinated. Given hepatitis B can be spread in many different ways, it is strongly advised that all household contacts and sexual partners should be vaccinated, as well as using condoms with sexual partners [4]. By the way, vaccination is usually free for the above groups [5].
​
If you are concerned you may have been put at risk of hepatitis B, or that you may have put someone else at risk, contact your GP or local sexual health clinic straight away. Your doctor can also contact a sexual partner for you, without including your details if you wish to stay anonymous.

Telling others about your diagnosis

After you have had time to come to terms with your diagnosis [6], you may wish to start thinking about disclosing your condition to others.There are many possible reasons for disclosure, such as:
  • one or more sexual partners have been possibly exposed to the virus during sex without a condom
  • you are embarking on a new relationship.

Knowing when and how to disclose can be difficult. Some people may be supportive, whereas others may withdraw or even be angry. Often this is due to their lack of knowledge about the condition. Be prepared that a relationship may change or even end.
​

Here are some tips that may help with the process [7]:
​
  • Make sure you know the basics about hepatitis B so you can answer some of the more common questions.
  • Before you speak to them, practise how the conversation might go with a good friend, considering both best and worst scenarios.
  • Choose a meeting place where you feel comfortable and safe. Face-to-face is usually best, rather than through email, for instance.
  • Ask them to keep your diagnosis confidential.
  • Bring something you can show like a leaflet or point them to a website like Hepatitis Australia or the National Hepatitis Infoline phone number 1800 437 222.
  • Give the person time and space to digest what you tell them.
  • Look after your own mental health during and after disclosing.​
Finally, you may find these insights help you to negotiate your own relationships and communicate your diagnosis.
“My personal philosophy and method is to be selective about the people I choose to date.  To me, it is important if the potential date has common sense and good character. Once I feel this person is worthy of my time and attention, I have the talk about my hepatitis B, and that HBV is vaccine preventable.  If they are interested in continuing a romantic relationship with me, they need to be vaccinated to protect against HBV.  Some may have already been vaccinated, and if so, HBV is no longer an issue.” 
​
​– Lindsey [1], member of the Hepatitis B Information and Support List, Hepatitis B Foundation blog
 “You need to approach dating, not as who will ‘accept’ you, but rather who ‘deserves’ you. Perspective is everything. If you see a health issue like HBV as a unique barrier to intimacy others will not understand and might reject you for, you will create self-defeating thoughts that not only limit your happiness, but are inaccurate. Everyone has issues. Whether it is health, mental, social or financial, we all feel alone at times and want a connection with another soul.”

​– Lindsey [1], member of the Hepatitis B Information and Support List, Hepatitis B Foundation blog
If you think this article might help someone else too, please like and share

References

  1. Hepatitis B Foundation. 2020. Dating and Hepatitis B – A Personal Perspective. [ONLINE] Available at: https://www.hepb.org/blog/dating-and-hepatitis-b-a-personal-perspective/. [Accessed 11 March 2020].
  2. DEPARTMENT OF HEALTH & HUMAN SERVICES Centers for Disease Control and Prevention. 2010. When Someone Close To You Has Chronic Hepatitis B. [ONLINE] Available at: https://www.cdc.gov/hepatitis/HBV/PDFs/HepBWhenSomeoneClose.pdf  [Accessed 24 February 2020].
  3. Hepatitis Australia. 2019. What is hepatitis B? [ONLINE] Available at: https://www.hepatitisaustralia.com/what-is-hepatitis-b  [Accessed 24 February 2020].
  4. Hepatitis B Foundation. 2020. Prevention Tips. [ONLINE] Available at: https://www.hepb.org/prevention-and-diagnosis/prevention-tips/  [Accessed 24 February 2020].
  5. Australian Government Department of Health. 2018. Hepatitis B immunisation service. [ONLINE] Available at: https://www.health.gov.au/health-topics/immunisation/immunisation-services/hepatitis-b-immunisation-service  [Accessed 24 February 2020].
  6. Hepatitis Australia. 2019. Dealing with your hepatitis B diagnosis. [ONLINE] Available at: https://www.hepatitisaustralia.com/dealing-with-your-hepatitis-b-diagnosis. [Accessed 24 February 2020].
  7. Hepatitis NSW. 2019. Hepatitis factsheet: Disclosure. [ONLINE] Available at: https://www.hep.org.au/wp-content/uploads/2019/11/Factsheet-Hep-disclosure.pdf. [Accessed 24 February 2020].
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Liver detox diets and Traditional Chinese Medicine: Do they work?

9/2/2020

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​First published on Hepatitis Australia's website in January 2020
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Image by marker_photography from Pixabay
​“Detox diets”, supplements and Traditional Chinese Medicine are marketed as beneficial for the liver, but do they work?
​
First let’s look at where the liver is and what it does.

Liver anatomy

Its functions include:
​
  • producing bile to help digest fats
  • making proteins for the blood
  • turning excess glucose into glycogen for energy storage and later release
  • regulating blood clotting
  • working as part of the immune system
  • breaking down toxins and drugs.

​Detox diets

Also known as a liver cleanse or flush, some people believe a detox diet helps remove excess waste after too much alcohol, unhealthy foods, or just for daily liver health. The first days may begin with fasting or drinking fluids only. Most detox diets take out processed food from your diet and may include commercial products, such as herbal supplements.
​
Some people feel better on these diets, often simply due to eating more healthily. This might cause them to believe that the liver cleanse works, but it’s important to consider the following:
​
  • If the diet requires drinking lots of juice and you have kidney disease or diabetes, this might be harmful. As some juices are high in sugar this can also be unhealthy for the average person.
  • If the diet involves fasting, you may feel dizzy and weak.
  • If you have liver damage from hepatitis B or C, this could worsen the damage [1,2].
  • Not enough scientific trials have been done on detox diets to advise on their safety and risks [3].​
​
For most people following a healthy lifestyle, the liver is well equipped to remove day-to-day toxins and you don’t need to do a detox.

​Supplements

Some studies in animals show milk thistle decreases liver inflammation, and turmeric protects against liver injury. However, there haven’t been enough studies done on humans to recommend their use in prevention of liver disease [4].

The US National Center for Complementary and Integrative Health (NCCIH) advises that milk thistle can cause allergic reactions in some people or low blood sugar in people living with diabetes [5].
​
We should also remember that detox products and liver supplements may not be standardised. Products could have different strengths and be of varying quality. Some may interact with medication or have side effects including causing liver damage.

Traditional Chinese Medicine

Traditional Chinese Medicine (TCM) views the liver in terms of vital energy (qi) and the storage of blood (xue). Together with the scheme of Yin Yang, TCM practitioners may diagnose liver disorders, and offer treatments like acupuncture or herbs [6].

There is no evidence that acupuncture helps people with liver conditions. However, it is relatively safe if performed correctly [7].

Because there have been very few good quality studies, we have no strong proof that Chinese herbal products work for liver health. Some products have also been found to have been contaminated with plant or animal material, drugs like the blood-thinner warfarin, and heavy metals like arsenic. Some products can even contain the wrong herbs, which may damage the liver [8].

Therefore, it is very important that you are confident of what is in the Chinese herbs you buy. If you decide to use Chinese herbs or other supplements, it is advisable that you talk to your doctor, especially if you have hepatitis B or C, or other chronic diseases.

Finally, the best way to look after your liver is maintain a healthy weight, follow a balanced diet, exercise regularly, minimise alcohol intake, and avoid smoking.
If you think this article might help someone else too, please like and share.

References

  1. 2018. Can a Detox or Cleanse Help Your Liver? [ONLINE] Available at: https://www.webmd.com/digestive-disorders/liver-detox#1 [Accessed 8 January 2020]2.
  2. 2020. Foods and Drugs to Avoid With Hepatitis C. [ONLINE] Available at: https://www.webmd.com/hepatitis/hep-c-foods-drugs-avoid#2 [Accessed 17 January 2020].
  3. Klein, A., 2015. Detox diets for toxin elimination and weight management: a critical review of the evidence. Journal of Human Nutrition and Dietetics, [Online]. 28(6), 675-86. Available at: https://www.ncbi.nlm.nih.gov/pubmed/25522674 [Accessed 8 January 2020].
  4. Johns Hopkins Medicine. 2020. Detoxing Your Liver: Fact Versus Fiction. [ONLINE] Available at: https://www.hopkinsmedicine.org/health/wellness-and-prevention/detoxing-your-liver-fact-versus-fiction [Accessed 8 January 2020].
  5. National Center for Complementary and Integrative Health. 2016. Milk Thistle. [ONLINE] Available at: https://nccih.nih.gov/health/milkthistle/ataglance.htm#hed2 [Accessed 8 January 2020].
  6. Chen, T., 1998. The liver in traditional Chinese medicine. Journal of Gastroenterology and Hepatology, [Online]. 13(4), 437-42. Available at: https://www.ncbi.nlm.nih.gov/pubmed/9641312 [Accessed 8 January 2020].
  7. National Center for Complementary and Integrative Health. 2020. Acupuncture: In Depth. [ONLINE] Available at: https://nccih.nih.gov/health/acupuncture/introduction [Accessed 8 January 2020].
  8. National Center for Complementary and Integrative Health. 2020. Traditional Chinese Medicine: What You Need To Know. [ONLINE] Available at: https://nccih.nih.gov/health/whatiscam/chinesemed.htm [Accessed 8 January 2020].
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Dealing with your hepatitis B diagnosis

27/9/2019

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​First published on Hepatitis Australia's website in September 2019.
If you’ve just been diagnosed with hepatitis B, it might help to know you’re not alone.
​
In 2018 there were 226,612 people in Australia (257 million people worldwide) living with hepatitis B.

Emotional reactions


​After being diagnosed with hepatitis, people can experience a range of reactions including shock and uncertainty, even if they had been expecting a positive test result.

It’s not uncommon to feel depressed, anxious, fearful, or worry about possible stigma. In addition, there may also be self-blame, guilt, or embarrassment.

Take your time working through difficult thoughts and emotions. Try to be patient and have self-compassion. Sometimes talking things through with your doctor or a counsellor can help.

Stigma


Stigma can arise in society or even within yourself. It can isolate you or interfere with you receiving treatment. For instance, a person may feel apprehensive about being seen attending an infectious diseases clinic if they are worried about what others might think.
​
A great way of reducing stigma is by learning more about hepatitis B. This will empower you to manage your condition together with your doctor, plus it’s helpful if you want to educate others.

The learning process

Be open to learning about hepatitis B at your own pace.
​
Feel free to explore the huge range of resources available such as via Hepatitis Australia. Information is available in other languages, audio/video formats including podcasts. There are also personal stories here and here about real people living with hepatitis B.

Support


Having the right support is invaluable. Who you share your diagnosis with is a very personal decision. No matter who your trusted person(s) is; you should reflect on the pros and cons of disclosure to each one.
​
You can also join a support group through your local hepatitis organisation or online forums like Hep Forums. Do keep in mind that forums may include people from other countries who have differing access to healthcare and medications, and that any health information should be discussed with your doctor.


Finally, these tips might be useful when you see your doctor.
​

Come prepared


Being prepared will help you get the most out of your appointment. Having a set of questions ready is a great way for you to get the information you need.

Don’t be afraid to ask questions


Here are some common questions others ask:
  • How did I get hepatitis B?
  • How do I make sure I don’t share it with others?
  • How will I know if I need treatment?
  • What will happen if I don’t agree to treatment?
  • What are the options for treatment?
  • What can I do to stay healthy and look after my liver?

Make notes for later


Research shows that people who are anxious or stressed are more likely to forget or incorrectly recall information later. So, it’s good to make notes during the appointment. Alternatively, ask your doctor for a written list of what you will both do after the appointment.

The right doctor for you


Because hepatitis B can be a lifelong condition, it’s ideal if you have a good and honest relationship with your doctor. Consider the following:
​
  • Do you feel comfortable talking to your doctor about your situation?
  • Does your doctor explain difficult terms, and answer your questions to your satisfaction?
  • Do they take time and not rush you?
  • Do they encourage you to take responsibility in your health management?
​
If you answered no to a few of these questions, then seeking a second opinion might be reasonable. If you need help to find a doctor with experience treating hepatitis B, you can call the National Hepatitis Infoline on 1800 437 222.
If you think this article might help someone else too, please like and share

References


  • Hepatitis Australia. 2019. Hepatitis Statistics. [ONLINE] Available at: https://www.hepatitisaustralia.com/hepatitis-statistics. [Accessed 31 August 2019].
  • The Multicultural HIV and Hepatitis Service. N.D. Hepatitis B Statistics. [ONLINE] Available at: https://www.mhahs.org.au/index.php/en/media-page/statistics/hepatitis-b-statistics. [Accessed 31 August 2019].
  • Valizadeh, L., 2016. Psychological Reactions among Patients with Chronic Hepatitis B: a Qualitative Study. Journal of Caring Sciences, [Online]. 5(1), 57–66. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794545/#R15[Accessed 31 August 2019].
  • Enescu, A., 2014. Psychosocial issues in patients with chronic hepatitis B and C. Current Health Sciences Journal, [Online]. 40(2), 93-6. Available at: https://www.ncbi.nlm.nih.gov/pubmed/25729588/[Accessed 31 August 2019].
  • Ng, C., 2013. Uncovering the experiences and needs of patients with chronic hepatitis B infection at diagnosis: a qualitative study. Asia-Pacific Journal of Public Health, [Online]. 25(1), 32-40. Available at: https://www.ncbi.nlm.nih.gov/pubmed/21807630[Accessed 31 August 2019].
  • Kessels, R., 2003. Patients' memory for medical information. Journal of The Royal Society of Medicine, [Online]. 96(5), 219–222. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC539473/[Accessed 31 August 2019].
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    Dr Alice Lam

    I'm a doctor who is passionate about writing quality health content.

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